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61999 Physiology

A 47-year-old man presents to his physician because he has noticed that his right breast is noticeably larger than his left breast. Breast examination demonstrates that the right breast is diffusely enlarged. The breast tissue is freely mobile and without distinct masses. The patient repos that the breast has been slowly enlarging over a period of several years. Which of the following is the MOST likely mechanism causing a relative excess of hormone leading to the breast enlargement in this patient?

ADecreased production of testosterone secondary to primary hypogonadism
BDrug that inhibits testosterone synthesis
CDrug with estrogen-like activity
DIncreased peripheral conversion of androgens to estrogens
Physiology
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62001 Pathology

A 60-year-old woman complains of weakness and hematuria. Physical examination shows marked pallor, hepatosplenomegaly, and numerous ecchymoses of the upper and lower extremities. A CBC reveals a normocytic normochromic anemia, thrombocytopenia, neutropenia, and a marked leukocytosis, which is composed mainly of myeloblasts. The major clinical problems associated with this patient’s condition are most directly related to which of the following?

AAvascular necrosis of bone
BDisseminated Intravascular Coagulation
CHypersplenism
DSuppression of Hematopoiesis
Pathology
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