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52525 Medicine

A male presenting with respiratory distress is put on a ventilator. Tracheal culture was obtained and sent for diagnosis. In the meanwhile, he was empirically staed on amikacin and ceftriaxone. Culture repo after 48 hrs shows growth of Klebsiella pneumoniae which is ESBL +ve on antimicrobial susceptibility testing. The modification needed in his antibiotic treatment is:

AReplace ceftriaxone with ceftazidime
BOmit amikacin and add a quinolone
CReplace ceftriaxone with imipenem
DContinue the same antibiotics at higher doses
Medicine
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