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49268 Gynaecology & Obstetrics

Rani a 24-year-old woman presents to her gynaecologist as she has chronic hypothyroidism and wants to conceive now. Her hypothyroidism is well controlled at 75 microgram of Thyroxine. She doesn&;t smoke or drink and doesn&;t have any other medical ailment. She would like to know if she should keep taking her Thyroxin. Which of the following is the best advice to give to this patient?

AStop taking Thyroxine and switch to methimazole as we would like to control your baby's thyroid levels
BThyroxine is safe during pregnancy but it is not absolutely necessary during pregnancy to continue thyroxine.
CThyroxine is not safe during pregnancy and it is better for your baby to be hypothyroid than hypehyroid
DThyroxine is safe in pregnancy and the dose of thyroxine would be increased during pregnancy to avoid hypothyroidism, which may affect the baby adversely (Correct Answer)
49274 Anaesthesia

A 70 kg old athlete was posted for surgery, Patient was administered succinylcholine due to unavailability of vecuronium. It was administered in intermittent dosing [total 640 mgi. During recovery patient was not able to respire spontaneously & move limbs. What is the explanation-

APseudocholinesterase deficiency increasing ,action of syccinylcholine
BPhase 2 blockade produced by succinylcholine (Correct Answer)
CUndiagnosed muscular dystrophy and muscular weakness
DMuscular weakness due to fasciculation produced by succinylcholine