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47275 Physiology

A gardener was accidentally poisoned by a weed killer that inhibits acetylcholinesterase. Which of the following alterations in neurochemical transmission at brain cholinergic synapses is the most likely result of this poisoning?

ABlockade of cholinergic receptors
BA pileup of choline outside the cholinergic neuron (in the synaptic cleft)
CA pileup of acetylcholine outside the cholinergic neuron (in the synaptic cleft) (Correct Answer)
DUp-regulation of postsynaptic cholinergic receptors