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40262 Surgery
40264 Pharmacology

A 44-year male has anxiety for which he was put on alprazolam therapy for 3 years. His family notices no improvement and he develops slurring of speech after taking few pegs of alcohol. He decided to stop using the drug to prevent dependence. He was admitted to hospital with severe withdrawal symptoms. Which is accurate statement for Alprazolam use :-

AAdditive CNS depression occurs with ethanol
BAbrupt discontinuance of alprazolam after 4 weeks of treatment may elicit withdrawal signs
CTolerance can occur with chronic use of any benzodiazepine
DAll of the above statements are accurate (Correct Answer)