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188141 Pathology

A 28 year old female teacher is found to have a prolonged bleeding time and normal platelet count. She had a bleeding of “easy bleeding” with frequent bleeding of the gums, epistaxis, cutaneous bleeding and menorrhagia, further testing revealed a deficiency of Von willebrand factor. Which of the following thrombogenic processes involving platelets is most directly impaired?

AAdhesion
BAggregation
CFormation of fibrinogen bridges
DConformational change with activation of phospholipid surface
Pathology
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