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176642 Pathology

A 14-year-old girl presents with a 5-day history of hypertension, oliguria, and hematuria. She was seen 2 weeks earlier for a severe throat infection with group A (b-hemolytic) streptococci. A kidney biopsy displays glomerulonephritis. Immunofluorescence staining for which of the following proteins would provide the strongest evidence that this patient’s glomerulonephritis is mediated by immune complexes?

AComplement
BFibrinogen
CHageman factor (clotting factor XII)
DPlasminogen
Pathology
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