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167647 Unknown

A 85-year-old male patient has been suffering from progressive memory loss over the last two years. She also needs help with her daily activities. MRI revealed diffuse coical and hippocampal atrophy in this patient. HPE in such conditions demonstrates the following findings. Which of the following drug used in the treatment of the above condition does not act by increasing acetyl choline levels in nucleus basalis of meyne?

ARivastigmine
BDonepezil
CMemantine
DTacrine
Unknown
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167648 Medicine

A 45 year old male known case of diabetes presents with nausea , multiple episodes of vomiting and abdominal pain.He is stuporous , having blood glucoselevel of 402 mg% and on urine examination Ketone bodies are detected.He is having tachycardina along with ohostatic hypotension. On lab investigation,his potassium levels are 3 meq/L.The next best step in the management will be:

AManage hypokalemia-Repeat serum K+ levels- IV fluids and sta IV regular insulin
BIV fluids-give IV regular insulin and lastly manage hypokalemia
CGive IV regular insulin along with K+ - IV fluids after the K+ level is normal
DIV fluids - give Lente insulin and side by side manage hypokalemia
Medicine
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167651 Pathology

A 45-year-old woman presents with a 6-month history of fatigue and swelling in her neck. Physical examination shows a goiter. A CBC discloses megaloblastic anemia and a normal reticulocyte count. Additionally, there is an elevated serum level of TSH and antithyroid antibodies. Needle aspiration of the left lobe of the thyroid reveals benign follicular cells and numerous lymphocytes. Anemia in this patient is most likely caused by antibodies directed to which of the following targets?

AChief cells
BIntrinsic factor
CPaneth cells
DTSH receptor
Pathology
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