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16062 Pharmacology

Which of the following statements regarding drugs used in leprosy is FALSE?

ASingle intramuscular injections of acedapsone maintain inhibitory levels of dapsone in tissues for upto 3 months
BMonthly doses of rifampicin delay the emergence of resistance to dapsone
CClofazimine should not be given to patients who are intolerant to dapsone or who fail to improve during treatment with dapsone (Correct Answer)
DClofazimine may cause changes in the skin colour
16063 Anaesthesia

A 60-kg, 53-year-old man with no significant medical problems undergoes lysis of adhesions for a small-bowel obstruction. Postoperatively, he has high nasogastric output and low urine output. What is the most appropriate management of his fluids?

AInfusion of D5 0.45% normal saline at 100 mL/h
BInfusion of D5 0.9% normal saline at 100 mL/h
CInfusion of D5 lactated Ringer at 100 mL/h
DReplacement of nasogastric tube losses with lactated Ringer in addition to maintenance fluids (Correct Answer)