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159911 Pathology

A newborn baby presented with a failure to pass meconium in the immediate postnatal period. The pediatrician also notices visible yet ineffective peristalsis, and abdominal distention. A radiological contrast enema demonstrated a narrow conical segment and a dilated proximal bowel. A diagnosis of Hirschsprung disease was made. Which of the following is a cause of the condition in the patient?

AFailure of migration of neural crest cells
BExcessive peristalsis of the affected pa of gut
CFailure of involution of vitelline duct
DObstruction secondary to an infectious agent
Pathology
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