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153724 Physiology

A clinical study is conducted to determine the actions of an unknown test solution on red blood cell volume. One milliliter of heparinized human blood is pipetted into 100 milliliters of test solution and mixed. Samples are taken and analyzed immediately before and at 1-second intervals after mixing. The results show that red blood cells placed into the test solution immediately swell and burst. Which of the following best describes the tonicity and osmolarity of the test solution?

AHypeonic; could be hyperosmotic, hypo-osmotic, or iso-osmotic
BHypeonic; must be hyperosmotic or hypo-osmotic
CHypeonic; must be iso-osmotic
DHypotonic; could be hyperosmotic, hypo-osmotic, or iso-osmotic
Physiology
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153728 Unknown

A 3 year old boy is recently diagnosed with Acute lymphoblastic leukemia/lymphoma. His peripheral blood film is shown below. A bone marrow biopsy is performed and reveals > 50 % lymphoblasts. Immunostaining reveals cells positive TdT. He is staed on chemotherapy. Few days later his condition deteriorated. The doctor on duty is suspecting that child may have developed tumor lysis syndrome. Which of the following electrolyte abnormality is not seen in the above condition?

AHyperuricemia
BHyperkalemia
CHypokalemia
DHypocalcemia
Unknown
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