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147814 Pathology

A 50-year-old woman presents with a painless soft tissue mass in her right thigh. Upon surgical excision, the surgeon notices that the tumor is adherent to the surrounding tissues. Histologic analysis reveals a neoplasm composed of pleomorphic clear cells, with vacuolated cytoplasm. The nucleus of many cells is indented by the cytoplasmic vacuoles, which are stained by histochemical methods for lipids. Which of the following is the most likely diagnosis?

AChondrosarcoma
BLipoma
CLiposarcoma
DMetastatic adenocarcinoma
Pathology
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