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146355 Pathology

A 7-year-old boy presented with generalized edema. Urine examination revealed marked albuminuria. Serum biochemical examinations showed hypoalbuminemia with hyperlipidemia. Kidney biopsy was undertaken. On light microscopic examination, the kidney appeared normal. Electron microscopic examination is most likely to reveal –

AFusion of foot processes of the glomerular epithelial cells
BRarefaction of glomerular basement membrane
CDeposition of electron dense material in the basement membrane
DThin basement membrane
Pathology
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146357 Medicine

A 75-year-old man is bought to the hospital because of a syncopal episode. There was no incontinence or post-event confusion. On examination, his blood pressure is 140/80 mm Hg, pulse 72/min with no postural changes. His second heart sound is diminished and there is a systolic ejection murmur that radiates to the carotids. With the Valsalva maneuver, the murmur decreases in length and intensity.For the above patient with a systolic murmur, select the most likely diagnosis.

Aaortic stenosis
Bhypertrophic obstructive cardiomyopathy (HOCM)
Cmitral regurgitation (chronic)
Dtricuspid regurgitation
Medicine
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