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142460 Unknown

A 5-month-old child presented to the dermatology OPD with dryness along with white, fine scales on most pas of the body with sparing of face. The child was born at 39 weeks gestation spontaneous vaginal delivery outside the hospital. On examination, large scales which were attached at the centre with turned up edges were observed at the extensor surface of lower limbs along characteristic finding on palms and deltoid region. Which of the following genes is most likely defective in the above condition: –

ADesmoglein
BPlakoglobin
CPlakophilin
DFilaggrin
Unknown
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