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131473 Pathology

A 60-year-old man presents with dizziness, nausea and severe shoness of breath of several months’ duration. Physical examination shows hepatomegaly, ascites and anasarca. His blood pressure is 200/115 mm Hg. An X-ray film of the chest demonstrates cardiomegaly and mild pulmonary edema. Although different mechanisms may have contributed to the pathogenesis of hypeension in this patient, the common end result for all of them is which of the following?

AAerial cystic medial necrosis
BDecreased plasma oncotic pressure
CGeneralized vasodilation
DIncreased peripheral vascular resistance
Pathology
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131477 Unknown

A recently diagnosed case of small cell carcinoma of lung presented with slowly progressive proximal muscle weakness along with ptosis of eyelids and diplopia. O/E: – DTRs-absent Autonomic dysfunctions like frequent dryness of mouth were present. The doctor advised repetitive nerve stimulation test. There was increase in compound muscle action potential amplitude and this increase was >100% following exercise or with high frequency repetitive nerve stimulation. On serological testing, antibodies will be found against which channels: –

AT-type of calcium channels
BP/Q type of calcium channels
CL type of calcium channels
DN- type of calcium channels
Unknown
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