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124482 Pathology

A 53-year-old woman discovers a lump in her breast and physical examination confirms a mass in the lower, outer quadrant of the left breast. Mammography demonstrates an ill-defined, stellate density measuring 1 cm. Needle aspiration reveals malignant ductal epithelial cells. A modified radical mastectomy is performed. The surgical specimen reveals a firm irregular mass (arrows). Which of the following cellular markers would be the most useful to evaluate before considering therapeutic options for this patient?

ACollagenase
BEstrogen receptors
CGalactosyltransferase
DLysosomal acid hydrolases
Pathology
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124486 Unknown

A 40-year-old male presented to the OPD with history of watery diarrhoea and periodic abdominal pain for 2 months. On examination, Warm face Face engorged with blood along with itching and sweating Diastolic murmur in the left 4th ICS parasternally which increases with inspiration Lab findings revealed increased 5-HIAA secretion in urine. Coloscopy was done. Biopsy of this mass was taken and it stained positive for chromogranin. With which of the following syndrome is the above condition may be associated: –

ASipple syndrome
BWermer syndrome
CNeurofibromatosis
DTuberous sclerosis
Unknown
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