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124059 Medicine

A 15-year-old boy presented with one day history of bleeding gum, subconjunctival bleed and purpuric rash. Investigations revealed following results: Hb- 6.4 gm/dL; TLC-1,00,000/microlitre, platelet 35,000/cubic millimetre; prothrombin time-20 sec with a control of 13 sec; paial thromboplastin time-50sec; and Fibrinogen lOmg/dL. Peripheral smear was suggestive of acute myeloblastic leukemia. Which of the following is the most likely?

Amyeloblastic leukemia without maturation
BMyeloblastic leukemia with maturation
CPromyelocytic leukema
DMyelomonocytic leukemia
Medicine
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124063 Pathology

A 25-year-old woman presents with a 2-week history of febrile illness and chest pain. She has an erythematous, macular facial rash and tender joints, particularly in her left wrist and elbow. A CBC shows mild anemia and thrombocytopenia. Corticosteroids are prescribed for the patient. The patient is noted to have increased serum levels of ceruloplasmin, fibrinogen, a2-macroglobulin, serum amyloid A protein, and C-reactive protein. Together, these markers belong to which of the following families of proteins?

AAcute phase proteins
BAnaphylatoxins
CInhibitors of platelet activation
DProtease inhibitors
Pathology
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