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120378 Pathology

A 25-year-old man involved in a motorcycle accident incurs a laceration to his thigh. The bleeding is stabilized en route to the hospital, but on arrival, he is noted to have orthostatic hypotension and his hematocrit is 21%. He receives 2 units of PRBCs. As the first unit is nearly finished transfusing, he becomes febrile and hypotensive. Urine output ceases. The serum above the clot in a red top phlebotomy tube is pink. Which of the following complications of transfusion has most likely occurred in this man?

ADonor antibodies were directed against his granulocytes
BDonor blood was contaminated with hepatitis C virus
CFluid overload led to congestive heart failure
DMislabeled specimens were processed in the laboratory
Pathology
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