Oxygen hemoglobin dissociation curve shifts to right in all of the following conditions EXCEPT:
Correct Answer: Decreased H+
Description: Ans. C Decreased H+Ref: Ganottg, 25th ed. pg. 640-641OXYGEN HEMOGLOBIN DISSOCIATION CURVE* Oxygen- hemoglobin dissociation curve is sigmoid 'S' shaped because binding of one oxygen molecule to heme increases the affinity of second heme molecule for oxygen and so on.Factors affecting affinity of Hb for oxygen and causing the shift of curve are:Left shiftRight Shift* This means the affinity of oxygen to Hb is increased and oxygen is bound more tightly to hemoglobin* This means the affinity of O2 to Hb is decreased which favours release of oxygen to tissue.* Factors leading to left shift are# Alkalosis or | pH# |pCO2 (CO2 ) content of blood)# |Temperature (Hypothermia)#| 2,3 DPG* Factors leading to right shift are:# Acidosis or | pH# | PCO2 (CO2 content of blood)# | Temperature (Hypothermia)# | 2,3 DPG
Category:
Physiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now