Oxygen consumption of whole human brain in ml per minute is about

**Core Concept**
The brain is a highly metabolic organ, requiring a significant amount of oxygen to maintain its functions. **Cerebral metabolism** and **oxygen consumption** are crucial for understanding neurological health and disease. The brain's high demand for oxygen is due to its intense neuronal activity.

**Why the Correct Answer is Right**
The correct answer reflects the brain's high metabolic rate, with oxygen being essential for **aerobic glycolysis** and the production of **ATP** in neurons. The brain accounts for only a small percentage of the body's mass but consumes a substantial portion of the body's oxygen supply. This high oxygen demand is necessary to support the brain's complex functions, including **synaptic transmission** and **neuronal signaling**.

**Why Each Wrong Option is Incorrect**
**Option A:** This option underestimates the brain's oxygen consumption, not reflecting its high metabolic demands.
**Option B:** Similarly, this option does not accurately represent the brain's significant oxygen requirements.
**Option D:** This option overestimates oxygen consumption, not aligning with established physiological values.

**Clinical Pearl / High-Yield Fact**
A key point to remember is that the brain's oxygen consumption is relatively constant, highlighting the importance of maintaining **cerebral perfusion** and oxygen supply to prevent **hypoxic injury**. This constant demand underscores the critical nature of ensuring adequate oxygenation in clinical settings.

**Correct Answer:** Correct Answer: C. 50 ml per 100g per minute