## Core Concept
The question pertains to the mechanism of action of hydroxyl ions as highly oxidizing free radicals in the context of bacterial destruction. Hydroxyl radicals (.OH) are a type of reactive oxygen species (ROS) known for their potent oxidative capabilities.
## Why the Correct Answer is Right
Hydroxyl ions, or more accurately hydroxyl radicals (.OH), are generated through the Fenton reaction or through the action of certain enzymes like myeloperoxidase in neutrophils. These radicals are highly reactive and can cause oxidative damage to cellular components, including DNA, proteins, and lipids, ultimately leading to bacterial death. The mechanism involves the abstraction of hydrogen atoms from these cellular components, leading to the formation of lipid peroxides, protein carbonyls, and DNA strand breaks.
## Why Each Wrong Option is Incorrect
- **Option A:** This option is blank and cannot be evaluated.
- **Option B:** This option is blank and cannot be evaluated.
- **Option C:** This option is blank and cannot be evaluated.
- **Option D:** This option is blank and cannot be evaluated.
## Clinical Pearl / High-Yield Fact
A key point to remember is that the production of reactive oxygen species, including hydroxyl radicals, is a critical mechanism by which phagocytic cells like neutrophils and macrophages kill ingested microbes. This process is often referred to as the respiratory burst. Defects in this pathway, such as in chronic granulomatous disease (CGD), lead to recurrent life-threatening infections due to the impaired ability to generate superoxides and subsequent ROS.
## Correct Answer Line
**Correct Answer: C.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.