Oxidative decarboxylation of pyruvate requires
Correct Answer: COASH
Description: Inside the mitochondria, pyruvate is oxidatively decarboxylated to acetyl CoA by pyruvate dehydrogenase (PDH). It is a multi-enzyme complex with 5 co-enzymes and 3 apo-enzymes.
The co-enzymes needed are:
Thiamine pyrophosphate (TPP)
Co-enzyme A (CoA)
FAD
NAD+
Lipoamide.
The enzyme part of the PDH complex is made up of three component enzymes.
Reference: Vasudevan 7th ed, pg 116
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now