Oxidation without oxygen leads to formation of which product –
Correct Answer: Lactate
Description: Ans. is 'c' i.e., Lactateo Final product of glycolysis in the absence of O2 (anerobic glycolysis) is lactate.Anaerobic glycolysiso It occurs in the absence of oxygen. The pyruvate is fermented (reduced) to lactate in single stage.o The reoxidation of NADH (formed in the glyceraldehyde-3-phosphate dehydrogenase step) by respiratory chain is prevented as same NADH is utilized at lactate dehydrogenase step. So, there is no net production of NADH. Thus, there is net gain of 2 ATP only.o Unlike pyruvate which is converted to acetyl CoA to enter into krebs cycle, lactate cannot be further utilized by further metabolic pathways. Thus, lactate can be regareded as dead end in glycolysiso Anaerobic glycolysis occurs in exercising skeletal muscle, RBCs, lens, some region of retina, renal medulla, testis and leucocytes.
Category:
Biochemistry
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