Osteogenesis imperfecta is due to

A. Defective synthesis of type I collagen

B. Growth hormone dysfunction

C. Inborn error of the methionine metabolism

D. Boney abnormality confined to the metaphysis

Correct Answer: Defective synthesis of type I collagen

Description: (Defective synthesis of type I collagen) (153-55-A)Osteogenesis Imperfecta (brittle bones) 1:20,000It is basically a connective tissue disorder (defective synthesis of type I collagen) heterogenous disorders1. Osteopenia2. Propensity to fracture3. Laxity of ligaments4. Blue sclerae5. Crumbling teeth or dentinogenesisType I collagen (Bone, ligament, tendon and skin)Type II collagen (Cartilage)Type III collagen (Blood vessels, muscle and skin)Humocvstinuria - is in bom error of methionine metabolism

Category: Orthopaedics

Share:

← Previous MCQ

Next MCQ →

Get More

Subject Mock Tests

Practice with over 200,000 questions from various medical subjects and improve your knowledge.

Attempt a mock test now

Mock Exam

Take an exam with 100 random questions selected from all subjects to test your knowledge.

Coming Soon

Get More

Subject Mock Tests

Try practicing mock tests with over 200,000 questions from various medical subjects.

Attempt a mock test now

Mock Exam

Attempt an exam of 100 questions randomly chosen from all subjects.

Coming Soon