Origin of pindborg tumour is:
Correct Answer: Stratum intermedium
Description: The Pindborg tumor is classified as an uncommon, benign, odontogenic neoplasm that is exclusively epithelial in origin. Some have suggested that the epithelial cells of the Pindborg tumor are reminiscent of the cells in the stratum intermedium layer of the enamel organ in tooth development. Some hypothesize that the Pindborg tumor arises from remnants of the primitive dental lamina found in the initial stage of odontogenesis, and these epithelial rests are the more likely true progenitor cell. The definite etiology of this neoplasm still remains enigmatic.
Key concept:
The tumor cells bear a close morphologic resemblance to the cells of the stratum intermedium of the enamel organ; however, some investigators have recently suggested that the tumor arises from dental lamina remnants based on its anatomic distribution in the jaws.
Ref: Shafer's textbook of oral pathology 7th edition page 283
Category:
Pathology
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