Organelle where H2O2 is produced and destroyed is-
## **Core Concept**
The question targets the understanding of cellular organelles involved in the production and degradation of hydrogen peroxide (H2O2), a reactive oxygen species (ROS). H2O2 is both produced and metabolized within specific organelles, playing a critical role in cellular redox balance.
## **Why the Correct Answer is Right**
Peroxisomes are organelles found in cells that are involved in the catabolism of fatty acids and amino acids. One of the byproducts of fatty acid oxidation and amino acid catabolism in peroxisomes is hydrogen peroxide (H2O2), a harmful ROS. Peroxisomes contain the enzyme **catalase**, which breaks down H2O2 into water (H2O) and oxygen (O2), thereby protecting the cell from oxidative damage. This dual role of producing and destroying H2O2 makes peroxisomes unique.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because, although mitochondria do produce ROS, including superoxides that can be converted into H2O2 by superoxide dismutase, they are not primarily known for H2O2 destruction.
- **Option B:** This is incorrect because the endoplasmic reticulum (ER) is involved in various functions such as protein folding, lipid synthesis, and detoxification but is not specifically known for H2O2 production or destruction.
- **Option C:** This option is incorrect because lysosomes are involved in digestion and recycling of cellular waste and do not play a primary role in H2O2 metabolism.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that **peroxisomal disorders**, such as Zellweger spectrum disorders, result from defects in peroxisome biogenesis or function, leading to accumulation of very-long-chain fatty acids and other toxic substances, highlighting the importance of peroxisomal function in cellular homeostasis.
## **Correct Answer:** . Peroxisome