**Core Concept**
Cephalosporins are a class of β-lactam antibiotics that work by inhibiting bacterial cell wall synthesis. They are broadly classified into generations based on their spectrum of activity, pharmacokinetics, and resistance patterns. Oral cephalosporins are a subset of this class, designed for use in treating infections outside the hospital setting.

**Why the Correct Answer is Right**
Oral cephalosporins are effective against a range of Gram-positive and some Gram-negative bacteria. They act by binding to penicillin-binding proteins (PBPs) on the bacterial cell wall, thereby inhibiting the cross-linking of peptidoglycan and ultimately leading to cell lysis and death. The correct oral cephalosporin option is **Cefpodoxime**, which has broad-spectrum activity and is used to treat various infections, including respiratory, urinary tract, and skin infections.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it is not a commonly used oral cephalosporin.
**Option B:** This option is incorrect as it is not an oral cephalosporin; it is typically administered intramuscularly or intravenously.
**Option D:** This option is incorrect as it is not a commonly used oral cephalosporin.

**Clinical Pearl / High-Yield Fact**
When choosing an oral cephalosporin, it is essential to consider the specific infection being treated and the local resistance patterns. Cefpodoxime is a good choice for treating infections caused by both Gram-positive and Gram-negative bacteria.

**Correct Answer:** C. Cefpodoxime