**Core Concept**
The question tests the understanding of **sympathetic ophthalmia** and **Vogt-Koyanagi-Harada (VKH) syndrome**, two conditions with complex **immunopathological** mechanisms. Both are associated with **inflammation** and **autoimmune** responses.
**Why the Correct Answer is Right**
The correct answer is linked to the fact that both conditions have an **autoimmune etiology**, where the body's immune system mistakenly attacks its own tissues. In sympathetic ophthalmia, this occurs after **penetrating eye injury**, leading to an immune response against **uveal antigens**. VKH syndrome is also characterized by an autoimmune response, involving **melanin-containing cells**.
**Why Each Wrong Option is Incorrect**
**Option B:** Injury is a precipitating factor for sympathetic ophthalmia but not a common feature that defines both conditions.
**Option C:** Uveitis is a manifestation of both conditions but not the underlying common feature.
**Option D:** Vitiligo is associated with VKH syndrome but not a common feature with sympathetic ophthalmia.
**Clinical Pearl / High-Yield Fact**
Remembering that both conditions involve an **autoimmune** response is crucial, as this underlies their pathogenesis and guides treatment approaches, often involving **immunosuppression**.
**Correct Answer:** a) Autoimmune etiology
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.