Proptosis is seen in – a) Neuroblastoma b) Meningioma c) Sympathetic ophthalmia d) Injuries
**Core Concept**
Proptosis is the anterior displacement of the globe of the eye, often caused by a space-occupying lesion or inflammation behind the eye. This can be due to various conditions that lead to an increase in orbital volume or mass.
**Why the Correct Answer is Right**
Among the given options, neuroblastoma is a type of cancer that originates in the adrenal glands but can also arise in the neck, chest, or pelvis. Proptosis can occur in neuroblastoma due to the presence of metastatic disease in the orbit, which can cause an increase in orbital volume or mass. This is often accompanied by other symptoms such as eyelid swelling, chemosis, and decreased vision.
**Why Each Wrong Option is Incorrect**
**Option A:** Neuroblastoma is indeed associated with proptosis, making it the correct answer. The other options do not have a direct association with proptosis.
**Option B:** Meningioma can cause proptosis, but it is not the most common cause among the given options. Meningiomas are typically benign tumors that arise from the meninges.
**Option C:** Sympathetic ophthalmia is a rare inflammatory condition that can occur after trauma or surgery to the eye, but it is not typically associated with proptosis.
**Option D:** Orbital injuries can cause proptosis, but they are not the most common cause among the given options.
**Clinical Pearl / High-Yield Fact**
Proptosis can be a sign of underlying malignancy, so it's essential to evaluate patients with proptosis thoroughly for systemic disease.
**Correct Answer:** a. Neuroblastoma