Post-operative vomiting is less and patient is able to ambulate soon with one of the following:
**Core Concept**
The question is referring to a pharmacological intervention that reduces post-operative nausea and vomiting (PONV) and facilitates early ambulation. This is a common concern in post-surgical patients, and several medications are used to address this issue.
**Why the Correct Answer is Right**
The correct answer is most likely a medication that has a rapid onset of action, is effective against PONV, and does not cause significant sedation or respiratory depression. These characteristics are crucial for early ambulation and minimizing hospital stay. A medication that fits this profile is ondansetron, a selective serotonin 5-HT3 receptor antagonist. Ondansetron works by blocking the action of serotonin at the 5-HT3 receptor in the chemoreceptor trigger zone (CTZ) of the brain, thereby reducing vomiting.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is likely a medication that is used for sedation or analgesia, such as fentanyl or midazolam, which can cause respiratory depression and delay ambulation.
**Option B:** This option might be a medication that is used for nausea, but it does not have a rapid onset of action or is not as effective against PONV as ondansetron.
**Option C:** This option is likely a medication that is used for pain management, such as acetaminophen or ibuprofen, which do not have a significant effect on PONV.
**Clinical Pearl / High-Yield Fact**
When choosing a medication for post-operative nausea and vomiting, consider the timing of administration, the mechanism of action, and the potential for side effects. Selective serotonin 5-HT3 receptor antagonists, like ondansetron, are often the first-line treatment due to their efficacy and safety profile.
**Correct Answer:** A. Ondansetron