% of thiopentone–used in induction –
**Core Concept**
Thiopentone is a barbiturate used for rapid induction of anesthesia. Its pharmacokinetics and pharmacodynamics play a crucial role in determining the ideal dosage for induction.
**Why the Correct Answer is Right**
Thiopentone is typically administered in a dose of 3-5 mg/kg to achieve rapid induction of anesthesia. This dose range allows for a rapid onset of action, which is essential for ensuring patient safety and comfort. The dose of 3-5 mg/kg is also sufficient to produce a smooth transition from consciousness to unconsciousness, making it an ideal choice for induction.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because thiopentone is not typically used in a dose of 1 mg/kg for induction. This dose would be too low to produce the desired effect.
**Option B:** This option is incorrect because thiopentone is not typically used in a dose of 10 mg/kg for induction. This dose would be too high and could lead to respiratory depression and other adverse effects.
**Option C:** This option is incorrect because thiopentone is not typically used in a dose of 2 mg/kg for induction. While this dose may be sufficient for some patients, it is generally lower than the recommended dose range of 3-5 mg/kg.
**Clinical Pearl / High-Yield Fact**
It's worth noting that the dose of thiopentone required for induction may vary depending on the individual patient's characteristics, such as age, weight, and underlying medical conditions. Therefore, it's essential to carefully titrate the dose and monitor the patient's response to ensure safe and effective anesthesia.
**Correct Answer: C. 3-5 mg/kg.**