**Core Concept**
Octreotide is a synthetic somatostatin analog used in the management of various conditions, including acromegaly, carcinoid syndrome, and certain types of tumors. It acts by mimicking the action of natural somatostatin, a hormone that inhibits the secretion of other hormones.
**Why the Correct Answer is Right**
Octreotide is used to control symptoms and slow the growth of tumors in conditions such as acromegaly, carcinoid syndrome, and gastroenteropancreatic neuroendocrine tumors (GEP-NETs). It works by binding to somatostatin receptors on the surface of these tumor cells, which leads to a decrease in the secretion of excess hormones and a reduction in tumor growth. Octreotide is also used to manage severe diarrhea and flushing associated with carcinoid syndrome.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because octreotide can be used to manage severe diarrhea associated with carcinoid syndrome.
**Option B:** Incorrect because octreotide can be used to slow the growth of GEP-NETs.
**Option C:** Incorrect because octreotide can be used to control symptoms and slow the growth of acromegaly.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that octreotide is not suitable for use in pheochromocytoma, as it can cause a paradoxical increase in catecholamine release, leading to a hypertensive crisis.
**Correct Answer:** D.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.