**Core Concept**
Vision 2020 is a global initiative launched by the World Health Organization (WHO) and the International Agency for the Prevention of Blindness (IAPB) to eliminate avoidable blindness by the year 2020. The initiative aims to improve eye care services, particularly in low- and middle-income countries, through the establishment of centers of excellence that provide high-quality eye care services, training, and research.

**Why the Correct Answer is Right**
The correct answer refers to the number of centers of excellence established under the Vision 2020 initiative. These centers serve as hubs for eye care services, training, and research, and play a crucial role in reducing avoidable blindness worldwide. The centers are equipped with modern facilities and staffed by skilled eye care professionals who provide high-quality services, including cataract surgery, pediatric eye care, and low vision services.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it does not provide a specific number of centers of excellence established under Vision 2020.
**Option B:** This option is also incorrect as it does not accurately represent the number of centers established under the initiative.
**Option C:** This option is incorrect as it is not a realistic number of centers of excellence established under Vision 2020.

**Clinical Pearl / High-Yield Fact**
Vision 2020 has been instrumental in improving eye care services in many countries, particularly in low- and middle-income countries. The initiative has also led to the development of new eye care technologies and treatments, which have improved outcomes for patients with eye diseases.

**Correct Answer: C. 300**