**Core Concept**
The Nottingham Histologic Score (NHS) is a widely used grading system to assess the histological features of breast cancer. It is a 3-part scoring system that evaluates tubular formation, nuclear pleomorphism, and the presence of mitoses in breast cancer tissue.
**Why the Correct Answer is Right**
The NHS specifically evaluates the tubular formation, nuclear pleomorphism, and the presence of mitoses in breast cancer tissue. This scoring system helps pathologists to differentiate between different types of breast cancer and predict the prognosis of the patient. The NHS is an important tool in the diagnosis and management of breast cancer.
**Why Each Wrong Option is Incorrect**
**Option A:** The NHS does include the evaluation of tubular formation, so this option is incorrect.
**Option B:** The NHS also evaluates the presence of mitoses, so this option is incorrect.
**Option C:** The NHS specifically evaluates nuclear pleomorphism, so this option is incorrect.
**Clinical Pearl / High-Yield Fact**
The Nottingham Histologic Score is an essential tool for pathologists to assess the histological features of breast cancer and predict the prognosis of the patient.
**Correct Answer: C.**
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