**Core Concept**
Scabies is a parasitic skin infection caused by the mite Sarcoptes scabiei, leading to intense itching, skin lesions, and burrows. The clinical features of scabies are characterized by a specific distribution of lesions, typically involving the finger webs, wrists, axillae, and genital areas.

**Why the Correct Answer is Right**
Scabies is caused by the female mite burrowing into the skin, laying eggs, and causing an allergic reaction. The resulting lesions typically exhibit a serpentine or linear arrangement, often accompanied by intense itching, particularly at night. The mite's burrows can be visualized as small, thread-like lines or tunnels in the skin, often accompanied by a characteristic "burrow sign."

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because the intense itching associated with scabies is a hallmark feature of the disease, often described as worse at night.
* **Option B:** This option is incorrect because the distribution of scabies lesions is typically limited to areas of high skin-to-skin contact, such as the finger webs, wrists, axillae, and genital areas.
* **Option C:** This option is incorrect because scabies can be diagnosed clinically, and the presence of a mite or egg in a skin scraping is not a requirement for diagnosis.

**Clinical Pearl / High-Yield Fact**
Scabies can be transmitted through close contact with an infected person, often through activities such as sharing bedding, towels, or clothing. It's essential to treat all close contacts simultaneously to prevent re-infestation.

**Correct Answer: D.**