Not a barrier contraceptive among the following is :
Correct Answer: Centchroman
Description: Centchroman Non-hormonal contraceptive pill It is a selective estrogen receptor modulator Centchroman is a synthetic nonsteroidal contraceptive taken as a 30 mg tablet, staed on the first day of menses and taken twice weekly for 12 weeks and weekly thereafter (half-life is 170 h). It does not prevent ovulation. It prevents implantation through endometrial changes. Centchroman is not teratogenic or carcinogenic, exes no pharmacological effect on other organs. The only side effect noted is prolonged cycles and oligomenorrhoea in 8% cases. This is due to prolonged proliferative phase. Pregnancy rate is 1.83 per 100 woman years. The drug can also be used as a postcoital pill, given in 60 mg dose within 24 h of coitus (two tablets repeated 12 h later with failure rate of 1%). It has been developed by Central Drug Research Institute, Lucknow, and has been released in India under the name of Saheli. side effects ---Headache, nausea, vomiting. ---Gain in weight. ---Does not protect against HIV and STD. ---Some delay in return of feility (up to 6 months). ---Prolonged use--hyperplasia and atypical endometrium. contraindications ---During 6 months of lactation. ---PCOD, hepatic dysfunction, cervical dysplasia, allergy to the drug. Reference: Shaw's Textbook of Gynaecology 16th edition page 278,279
Category:
Gynaecology & Obstetrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now