Normal protein excretion in urine(daily):
Correct Answer: 90-120 mg
Description: The amount of protein in the urine is normally <150 mg/day.([?]90-120 mg) Protein handling at the glomerular filtration barrier : The endothelium is fenestrated (contains holes) and is freely permeable to water, small solutes, and most proteins; but not permeable to the blood cells. The basement membrane is a porous matrix of negatively charged proteins.The basement membrane is primarily considered as a charge-selectivity barrier; The processes of the podocytes interdigitate to cover the basement membrane and are separated by gaps called filtration slits. .They function primarily as the size-selective filter. It should also be noted that ~ Normally, the filtered proteins are almost entirely reabsorbed in the PCT; only a small quantity thus may appear in the urine.
Category:
Physiology
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