Normal GFR is
**Core Concept**
Glomerular filtration rate (GFR) is a critical measure of kidney function, indicating the rate at which the kidneys filter waste products from the blood. Normal GFR varies with age, sex, and body surface area, but typically ranges between 100-120 mL/min/1.73m^2 in adults.
**Why the Correct Answer is Right**
The correct answer is based on the formula for calculating GFR, which takes into account the serum creatinine concentration, age, sex, and weight of the individual. In adults, a normal GFR is typically considered to be above 90 mL/min/1.73m^2, with values ranging from 100-120 mL/min/1.73m^2 being considered normal. This range is based on the Cockcroft-Gault equation, which is widely used to estimate GFR.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because a GFR of 50 mL/min/1.73m^2 is below the normal range and may indicate chronic kidney disease (CKD).
* **Option B:** This option is incorrect because a GFR of 150 mL/min/1.73m^2 is above the normal range and may indicate hyperfiltration or other kidney disorders.
* **Option C:** This option is incorrect because a GFR of 0 mL/min/1.73m^2 is not a valid value, as it would indicate complete kidney failure.
**Clinical Pearl / High-Yield Fact**
A GFR of <60 mL/min/1.73m^2 is considered an indicator of moderate CKD, which may require treatment to slow disease progression and prevent complications.
**Correct Answer:** C. 120