Which of the following can cause both cicatricial as well as noncicatrical alopecia ?
**Core Concept**
Cicatricial and noncicatricial alopecia refer to two distinct forms of hair loss, differing in their underlying pathophysiology and clinical presentation. Cicatricial alopecia is characterized by scarring hair loss due to inflammation, whereas noncicatricial alopecia is characterized by hair loss without scarring. Both forms can result from various dermatological conditions.
**Why the Correct Answer is Right**
Lichen planopilaris (LPP) is a form of cicatricial alopecia that can cause scarring hair loss, but it can also present as noncicatricial alopecia in its early stages. The condition is characterized by inflammation of the hair follicles, leading to scarring and permanent hair loss. LPP is an autoimmune disease, and its pathophysiology involves the activation of T lymphocytes and the release of cytokines, which cause inflammation and damage to the hair follicles.
**Why Each Wrong Option is Incorrect**
**Option A:** Discoid lupus erythematosus (DLE) is a form of cicatricial alopecia, but it typically presents with distinct, coin-shaped lesions on the scalp, which are not always associated with noncicatricial alopecia.
**Option B:** Alopecia areata is a noncicatricial alopecia that presents with patchy hair loss, but it does not typically cause scarring.
**Option C:** Androgenetic alopecia is a noncicatricial alopecia that presents with hair thinning and loss, but it does not cause scarring.
**Option D:** Traction alopecia is a noncicatricial alopecia that presents with hair loss due to mechanical stress, but it does not cause scarring.
**Clinical Pearl / High-Yield Fact**
Lichen planopilaris can present with a wide range of clinical features, from mild, noncicatricial alopecia to severe, scarring alopecia. Early recognition and treatment are essential to prevent permanent hair loss.
**Correct Answer:** . Lichen planopilaris