Non-erosive arthritis is characteristic of:
Correct Answer: SLE
Description: Ans: A (SLE) Ref: Harrison s Principles of Internal Medicine 18th edition, pg 2728Explanation:SLE causes non erosive polyarthritis of the hands, wrist & knees.Can cause avascular necrosis of joints increased by steroid use.Psoriasis, RA & gout cause erosive arthritis. Psoriatic arthritis (PsA):DIP involved, nail changes ( pitting, ridging, onycholysis, yellow discoloration, hyperkeratosis) dactylitisAsymmetrical oligoarthritisSymmetrical polyarthritisArthritis mutilans with destruction and telescoping of digitsCASPAR criteria used to diagnose PsATreatment: Anti-TNF-a- infliximab, etanercept, adalimumab, golimumabAnti T cell- AlefaceptNewer agent- UstekinumabMethotrexate, sulfasalazine, leflunomideRheumatoid Arthritis (RA):MCP. PIP, &MTP involvedJuxta-articular osteopenia- earliest radiological findingACR & EULAR revised criteria used to diagnose RATreatment: Anti TNF- a- Infliximab. Etanercept. adalimumab, golimumab, certolizumabAbatacept, anakinra, rituximab, tocilizumabGouty arthritis:Acute, monoarthritis, 1st MTP involvedPrecipitated by diet, trauma, surgery, alcohol, stressJoint aspirate for needle shaped MSU crystals, birefringent with negative elongation. TC 2-60 thousandS.uric acid can be low /normal during attackAcute attack-NSAlDS, Colchicine, steroids, anakinraHypouricemic drugs- Allopurinol, febuxostat. Rasburicase. Pegloticase
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now