Antidepressant drug that can cause neuroleptic malignant syndrome and tardive dyskinesia is:-
**Core Concept**
The question tests the knowledge of a specific class of antidepressant medications that can cause severe side effects, including neuroleptic malignant syndrome (NMS) and tardive dyskinesia (TD). These conditions are rare but life-threatening and require immediate medical attention.
**Why the Correct Answer is Right**
The correct answer is a type of antidepressant that can cause NMS and TD due to its mechanism of action. This class of drugs is known to block dopamine receptors, which can lead to an imbalance in the brain's reward and motor control systems. The blockade of dopamine receptors can cause an increase in dopamine release, leading to the development of NMS and TD. The specific drug in question is a tricyclic antidepressant (TCA) that also has anticholinergic and antihistaminic properties.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it is a selective serotonin reuptake inhibitor (SSRI), a different class of antidepressants that is not typically associated with NMS and TD.
**Option B:** This option is incorrect because it is a monoamine oxidase inhibitor (MAOI), which is not commonly linked with NMS and TD.
**Option C:** This option is incorrect because it is a serotonin-norepinephrine reuptake inhibitor (SNRI), a class of antidepressants that is not typically associated with NMS and TD.
**Clinical Pearl / High-Yield Fact**
It is essential to note that all antidepressants carry a risk of NMS and TD, but the risk is higher with certain classes, such as TCAs. Therefore, it is crucial to monitor patients closely for these side effects and consider alternative treatments if necessary.
**Correct Answer:** C. Amitriptyline