Drug of choice for a child with first episode nephrotic syndrome is?
**Core Concept**
The underlying principle being tested is the management of **nephrotic syndrome**, a condition characterized by significant **proteinuria**, **hypoalbuminemia**, and **edema**. The primary goal is to reduce proteinuria and manage edema.
**Why the Correct Answer is Right**
The correct answer is based on the standard treatment protocol for nephrotic syndrome, which typically involves the use of **corticosteroids** as the first-line treatment to induce remission. **Prednisone** is commonly used due to its efficacy in reducing proteinuria and managing symptoms.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because while other immunosuppressants may be used in steroid-resistant cases, they are not the first choice.
**Option B:** Incorrect as it is not typically used for initial treatment of nephrotic syndrome.
**Option D:** Incorrect because it is not the preferred initial treatment for a first episode of nephrotic syndrome.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that **corticosteroids** are the mainstay of treatment for the first episode of nephrotic syndrome, with **prednisone** being a common choice due to its effectiveness.
**Correct Answer:** D. Prednisone.