Neostigmine antagonizes nondepolarizing blockade by all of the following mechanisms, except ?
Correct Answer: Increasing the release of Acetylcholine at the motor end plate
Description: Ans. is 'c' i.e., Increasing the release of Acetylcholine at the motor end palate o Anticholinestrases act by inhibiting the action of acetylcholinesterase (an enzyme that degrades acetylcholine by causing its hydrolysis). o Anticholinesterases thus increase the level of acetylcholine at the neuromuscular junction. o Neostigmine also has some additional direct action on cholinergic receptors i.e., it depolarizes motor end plate. o It does not increase the release of ACH. Accumulated ACH acts on prejunctional muscarinic autoreceptors and inhibits the release of ACH.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now