Neostigmine –
Correct Answer: It is a quaarnary amounium compound
Description: Ans. is `a' i.e., It is a quaarnary amounium compound Teiary amine Vs quaenary ammonium compound o Neostigmine is a quaenary ammonium compound. o Quaenary ammonium compounds are lipid insoluble and diffuse poorly across the membrane : - Li Oral absorption ---> Poor CNS penetration --> poor No CNS action Applied to eye No penetration of cornea. More marked effect on skeletal muscles, ganglia, but muscarinic effects are less prominant. o In contrast, physostigmine is a teiary amine derivated. o Teiary amine compounds are lipid soluble and diffuse easily across the membrane :- Oral absorption Good CNS penetration --> Good Produce CNS actions. Applied to eye --> Penetrate cornea. More marked muscarinic and CNS effect.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now