**Core Concept**
Toxic Epidermal Necrolysis (TEN) is a rare, life-threatening skin condition characterized by widespread skin necrosis and detachment, often triggered by medications. It represents a severe form of drug reaction with eosinophilia and systemic symptoms (DRESS).

**Why the Correct Answer is Right**
TEN is a form of Stevens-Johnson Syndrome (SJS) that involves more than 30% of the body surface area. It is caused by a severe immune-mediated reaction to medications, leading to the activation of neutrophils and the release of pro-inflammatory cytokines. This results in the destruction of keratinocytes and the detachment of the epidermis from the dermis.

**Why Each Wrong Option is Incorrect**
**Option A:** Erythema Multiforme - This is a separate condition that presents with targetoid lesions and mucosal involvement but does not involve widespread skin necrosis.
**Option B:** DRESS Syndrome - While DRESS is a form of drug reaction with eosinophilia, it typically involves less skin involvement and more systemic symptoms.
**Option C:** Staphylococcal Scalded Skin Syndrome - This is a condition caused by staphylococcal toxins that cause skin blistering and necrosis, but it is not a form of TEN.

**Clinical Pearl / High-Yield Fact**
TEN is a medical emergency that requires immediate withdrawal of the offending medication and admission to a burn unit for management.

**Correct Answer:** C.