NA hich of the 10110N% ing is not a cause of point mutation
**Core Concept**
Point mutations are changes in a single nucleotide in the DNA sequence of an individual. These mutations can occur due to various factors, including errors during DNA replication, exposure to mutagenic agents, or inherited genetic disorders. Point mutations can be categorized into different types, including transitions, transversions, and insertions or deletions.
**Why the Correct Answer is Right**
The correct answer is a type of mutation that is not a point mutation. Point mutations involve a change in a single nucleotide, whereas the correct answer involves a larger alteration in the DNA sequence. This can lead to significant changes in the protein structure and function, often resulting in disease.
**Why Each Wrong Option is Incorrect**
**Option A:** Transitions are a type of point mutation that occurs when a purine is replaced by another purine or a pyrimidine is replaced by another pyrimidine (e.g., A to G or C to T). This is a point mutation.
**Option B:** Transversions are a type of point mutation that occurs when a purine is replaced by a pyrimidine or vice versa (e.g., A to T or G to C). This is a point mutation.
**Option C:** Frameshift mutations are a type of mutation that occurs when one or more nucleotides are inserted or deleted from a DNA sequence, leading to a change in the reading frame of the genetic code. This is not a point mutation.
**Clinical Pearl / High-Yield Fact**
It is essential to remember that point mutations can occur due to various factors, including environmental exposures, genetic predisposition, and errors during DNA replication. Understanding the different types of mutations is crucial for identifying the underlying cause of genetic disorders.
**Correct Answer: C. Frameshift mutations are a type of mutation that occurs when one or more nucleotides are inserted or deleted from a DNA sequence, leading to a change in the reading frame of the genetic code.