Mytonic dystrophy is due to-

Correct Answer: CTG triple nucleotide repeat mutation
Description: Answer-C. CTG triple nucleotide repeat mutationMyotonic dystrophy is associated with a trinucleotide CTG repeat expansion on chromosome 19.This expansion affects the mRNA for the dystrophila myotonia protein kinase (DMPK).Triple nucleotide repeat mutations Normally, a codon is triplet (trinucleotide) (e.g. for CGG it is 5-50 and CGG triplet codon can be repeated, at a stretch, 5-50 times) Non-coding region
Category: Medicine
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