Pathology Mutation of which of the following gene is most impoant in paroxysmal nocturnal hemaglobinuria? A Decay accelerating factor (DAF) B Membrane inhibitor of reactive lysis (MIRL) C Glycosyl phosphatidyl inositol (GPI) D CD8 binding protein 💡 Explanation Mutation of which of the following gene is most impoant in paroxysmal nocturnal hemaglobinuria? ✓ Correct Answer: C. Glycosyl phosphatidyl inositol (GPI)