**Core Concept**
Succinylcholine is a depolarizing muscle relaxant that works by mimicking the action of acetylcholine at the neuromuscular junction, leading to sustained depolarization of the muscle cells. This results in muscle paralysis. In neonates, succinylcholine is particularly useful due to its rapid onset and short duration of action.
**Why the Correct Answer is Right**
Succinylcholine is the ideal muscle relaxant for neonates undergoing surgery for biliary atresia because it has a rapid onset of action, allowing for quick intubation, and a short duration of action, minimizing the risk of prolonged paralysis. Additionally, succinylcholine is metabolized by pseudocholinesterase, which is present in adequate amounts in neonates, making it a safe choice for this population.
**Why Each Wrong Option is Incorrect**
**Option A:** Rocuronium is a non-depolarizing muscle relaxant with a slower onset of action compared to succinylcholine, making it less ideal for rapid intubation in neonates.
**Option B:** Vecuronium is another non-depolarizing muscle relaxant with a slower onset of action and a longer duration of action compared to succinylcholine, making it less suitable for neonatal anesthesia.
**Option C:** Atracurium is a non-depolarizing muscle relaxant that undergoes Hofmann elimination, a process that is independent of liver and kidney function, making it a safer choice in patients with renal or hepatic dysfunction. However, it is not the ideal choice for neonates due to its slower onset of action.
**Clinical Pearl / High-Yield Fact**
When using succinylcholine in neonates, it is essential to be aware of the risk of hyperkalemia, which can occur due to the release of potassium ions from muscle cells during depolarization.
**Correct Answer:** A. Succinylcholine
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.