Murmur increasing with Valsalva manouvre
**Core Concept**
A Valsalva maneuver is a technique used to increase intrathoracic pressure, typically by forced expiration against a closed glottis. The resulting increase in intrathoracic pressure affects the dynamics of blood flow through the heart, particularly in the context of cardiac murmurs. The Valsalva maneuver can either increase or decrease the intensity of a murmur, depending on the underlying pathophysiology.
**Why the Correct Answer is Right**
A murmur that increases with the Valsalva maneuver is typically associated with aortic regurgitation. During the Valsalva maneuver, the increased intrathoracic pressure reduces the stroke volume and forward flow through the aortic valve, allowing more blood to flow back into the left ventricle through the incompetent aortic valve. This increased regurgitant flow is responsible for the intensification of the aortic regurgitation murmur.
**Why Each Wrong Option is Incorrect**
**Option A:** This option would be incorrect because murmurs associated with mitral stenosis typically decrease in intensity with the Valsalva maneuver. The reduced left ventricular volume and decreased forward flow through the mitral valve during the Valsalva maneuver decrease the intensity of the murmur.
**Option B:** This option is incorrect because murmurs associated with hypertrophic obstructive cardiomyopathy (HOCM) typically decrease in intensity with the Valsalva maneuver. The reduced left ventricular volume and decreased forward flow through the narrowed left ventricular outflow tract during the Valsalva maneuver decrease the intensity of the murmur.
**Option C:** This option is incorrect because murmurs associated with ventricular septal defects (VSDs) typically decrease in intensity with the Valsalva maneuver. The reduced left ventricular volume and decreased forward flow through the VSD during the Valsalva maneuver decrease the intensity of the murmur.
**Clinical Pearl / High-Yield Fact**
The Valsalva maneuver can be used clinically to differentiate between aortic regurgitation and other conditions that cause murmurs, such as mitral stenosis or HOCM. A murmur that increases in intensity with the Valsalva maneuver is highly suggestive of aortic regurgitation.
**Correct Answer:** B. Aortic regurgitation murmur.